WebSTAT3 acts as a pro-oncogenic factor in different cancers, including NSCLC, controlling the expression of specific genes involved in cell cycle progression, cell survival, angiogenesis, and immune response regulation. 4 Recent studies revealed that STAT3 activation in tumor cells occurs via the CAF release of interleukins (ILs), as IL6 and IL11 ... WebAug 22, 2014 · The present study examined the effects of Erk1/2 modulation on STAT3 signaling and cell growth in OSCC cells. Constitutive expression levels of phosphorylated (tyrosine and serine) and total STAT3, Erk1/2 and cyclin D1 were assessed in OSCC cell lines. Erk1/2 modulation was achieved by pharmacological agents; siRNA silencing …
PathScan® Total Stat3 Sandwich ELISA Kit - Cell …
WebPhosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation, and DNA binding (4). Stat1 protein exists as a pair of isoforms, Stat1α (91 kDa) and the splice variant Stat1β (84 kDa). In most cells, both isoforms are activated by IFN-α, but only Stat1α is activated by IFN-γ. WebPolyclonal Antibody for studying STAT3. Cited in 678 publications. Validated for WB, IP, IHC, ChIP. Highly specific and rigorously validated in-house, Stat3 Antibody (CST … nottalone senior mental health lead training
STAT3 silencing by an aptamer-based strategy hampers the …
WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-STAT3 (phospho S727) antibody [E121-31] (ab32143) Research with confidence – consistent and reproducible results with every batch. Long … WebThe PathScan ® Total Stat3 Sandwich ELISA Kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of Stat3 protein. A Stat3 rabbit mAb has been coated … The amount of immunoprecipitated DNA in each sample is represented as signal relative to the total amount of input chromatin, which is equivalent to one. Show More. Western blot analysis of extracts from HeLa cells, untreated or IFN-alpha treated (100 ng/ml for 5 min.), using Stat3 Antibody (left) or Phospho-Stat3 (Tyr705) Antibody #9131 (right). how to ship dinner plates